Hyaluronic Acid

What is it?

A polysaccharide, hyaluronic acid occurs in high concentrations in the skin, joints, and eyes, where it provides lubrication and sustains tissue hydration. Like many other ingredients we select, hyaluronic acid naturally declines as we age.


  • Boost skin moisture
  • Improve skin suppleness and reduce skin texture
  • Speeds up wound healing
  • Lubricate joints, reducing pain and inflammation
  • Supports better sleep
  • Reduce eye dryness

    Summary of Select Clinical Studies:

    • Reduction in wrinkle depth and volume, as well as improved skin luster and suppleness, after 12 weeks
    • Significant reduction in inflammation in joints
    • Improves sleep quality
    • Significantly improves skin moisture content immediately (see chart)


      1.  Oe, Mariko et al. “Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period.” Clinical, cosmetic and investigational dermatology vol. 10 267-273. 18 Jul. 2017, doi:10.2147/CCID.S141845
      2. Nelson, F R et al. “The effects of an oral preparation containing hyaluronic acid (Oralvisc®) on obese knee osteoarthritis patients determined by pain, function, bradykinin, leptin, inflammatory cytokines, and heavy water analyses.” Rheumatology international vol. 35,1 (2015): 43-52. doi:10.1007/s00296-014-3047-6
      3.  Jensen, Gitte S et al. “Oral intake of a liquid high-molecular-weight hyaluronan associated with relief of chronic pain and reduced use of pain medication: results of a randomized, placebo-controlled double-blind pilot study.” Journal of medicinal food vol. 18,1 (2015): 95-101. doi:10.1089/jmf.2013.0174
      4.  Kawada, Chinatsu et al. “Ingested hyaluronan moisturizes dry skin.” Nutrition journal vol. 13 70. 11 Jul. 2014, doi:10.1186/1475-2891-13-70

        No more pills and powder

        GEST, short for inGEST, was formed by three best friends on a mission to create thoughtful supplements that make our world healthier and wealthier.

        Like many people reading this right now, the three of us struggled with skin issues and approached the concept of aging skin with a vague sense of anticipation and confusion. In our path towards wellness, we attempted clean diets, nearly half of the product catalogs at Sephora and Target, and of course, skin supplements.

        After two years of experimenting with skin supplements, we were thousands of dollars poorer and had little to show for it other than bad reactions with acne flares and even digestive issues. Supplements really do suck, we thought. But, our minds changed when we stopped searching for miracles cures and instead learned to ignore false marketing and instead focused on studying the science behind the supplements.

        Guess what? Dietary supplements really do work, gigabytes of lab data and research prove so (our own glowing skin, hair, nails agree). The market is just saturated with not-so-great products that are heavy on marketing and light on substance.

        That’s where SKINMUNE comes in. A great skin supplement only works when it’s the right formulation with correct dosages of active ingredients, and when consumed as a routine. We are so excited to bring to you SKINMUNE, which was formulated with experts and developed over the course of a year working closely with our early beta users.

        We’ve combined the best clinically-proven ingredients to launch GEST SKINMUNE (skin + immunity). The first formula of its kind, sip these daily to see supple, plump, hydrated skin.